Ultrastructure of double minutes from a human tumor cell line.

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Ultrastructure of double minutes from a human tumor cell line

Double minutes (dm) have been isolated from human tumor cells by zonal centrifugation and by differential pelleting of chromosome suspsension. These methods allowed collection of dm in sufficient quantity and purity for visualization with electron microscopy. Ultrastructurally, the chromatin fibers in dm resemble thrance fragments was found. When the two isolation protocols were compared, diffe...

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Cell lines from human colon carcinoma with unusual cell products, double minutes, and homogeneously staining regions.

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1979

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.83.3.663